In other situations like strep or mono, the test specifically looks for unique proteins that identify the germ (and ignores all other germs that may be present; for example, if a patient has a staph tonsillitis and a strep test is formed, the strep test will come back "normal").
In contrast, rather than "growing" out the germ or testing for a specific germ protein, molecular diagnostic testing determines what germs are present by sequencing ALL the DNA that is found within a swab specimen. Using PCR, all the DNA within a specimen is sequenced and than compared to a database of over 25,000 different microbes including viruses, fungus, and bacteria. A report is than provided listing ALL the germs within a specimen along with the germ amount and what antibiotic would work best to treat.
Antibiotic resistance is determined through identification of any DNA genes that confer such resistance for the germ of interest.
A sample report is shown below...